Not known Factual Statements About akorn promethazine codeine

Not known Factual Statements About akorn promethazine codeine

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Due to the dangers of addiction, abuse, and misuse with opioids, even at advisable doses [see Warnings and Precautions (5.one)], reserve promethazine HCl and codeine phosphate oral Resolution to be used in Grownup sufferers for whom the key benefits of cough suppression are anticipated to outweigh the pitfalls, As well as in whom an enough assessment of the etiology from the cough is designed.

g., amiodarone, quinidine) could cause a rise in codeine plasma concentrations along with a reduce in Lively metabolite morphine plasma concentration which could cause an analgesic efficacy reduction or indicators of opioid withdrawal.

All information and facts presented Here's not meant in its place for or alternate to data from well being treatment practitioners. You should consult your health care Experienced about opportunity interactions or other doable problems just before utilizing any products. The Federal Foodstuff, Drug, and Cosmetic Act require this detect.

Codeine is known to get considerably excreted from the kidney, and the potential risk of adverse reactions to this drug may be increased in sufferers with impaired renal function.

Lifetime-threatening respiratory challenges (respiratory melancholy). Promethazine Hydrochloride and Codeine Phosphate Oral Solution can result in respiration difficulties (respiratory despair) which will come about Anytime all through cure and can result in Dying. Your risk of respiration issues is biggest when you first start out taking Promethazine Hydrochloride and Codeine Phosphate Oral Resolution, are having other medicines that could cause respiratory problems, have specific lung challenges, are aged or have particular other health issues.

The use of codeine in promethazine HCl and codeine phosphate oral Resolution may obscure the diagnosis or medical program of patients with acute abdominal situations.

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This may be affiliated with a lower in efficacy, and in a few individuals, may well lead to symptoms and signs and symptoms of opioid withdrawal.

Treatment method of Overdose Remedy of overdosage is driven by the overall clinical presentation, and includes discontinuation of promethazine HCl and codeine phosphate oral Alternative together with institution of acceptable therapy. Give Most important attention into the reestablishment of sufficient respiratory exchange via provision of a patent and protected airway along with the institution of assisted or managed air flow.

The next significant adverse reactions are described, or described in greater depth, in other sections:

This will come about Even when you acquire Promethazine Hydrochloride and Codeine Phosphate Oral Option particularly as prescribed by your Health care provider. Your risk of dependancy, abuse, akorn codeine and misuse is elevated when you or a member of the family incorporates a heritage of drug or Alcoholic beverages abuse or dependancy, or mental health issues.

Avoid the use of promethazine HCl and codeine phosphate oral Remedy in sufferers that are taking inhibitors of CYP2D6.

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These prescription drugs can be used to deal with and end ulcers while in the tummy, help with bowel syndrome, soften the stool, reduce constipation, or assist with large blood pressure.